ConsensusMapNormalizerAlgorithmMedian.h

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// $Maintainer: Johannes Veit $
// $Authors: Johannes Junker $
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#pragma once

#include <OpenMS/KERNEL/ConsensusMap.h>
#include <OpenMS/ANALYSIS/MAPMATCHING/ConsensusMapNormalizerAlgorithmThreshold.h>

namespace OpenMS
{

  class OPENMS_DLLAPI ConsensusMapNormalizerAlgorithmMedian
  {
    friend class ConsensusMapNormalizerAlgorithmThreshold;

private:
    ConsensusMapNormalizerAlgorithmMedian(const ConsensusMapNormalizerAlgorithmMedian & copyin);

    ConsensusMapNormalizerAlgorithmMedian & operator=(const ConsensusMapNormalizerAlgorithmMedian & rhs);

public:
    ConsensusMapNormalizerAlgorithmMedian();

    virtual ~ConsensusMapNormalizerAlgorithmMedian();

    enum NormalizationMethod { NM_SCALE, NM_SHIFT };

    static void normalizeMaps(ConsensusMap & map, NormalizationMethod method, const String& acc_filter, const String& desc_filter);

    static Size computeMedians(const ConsensusMap & map, std::vector<double> & medians, const String& acc_filter, const String& desc_filter);

    static bool passesFilters_(ConsensusMap::ConstIterator cf_it, const ConsensusMap& map, const String& acc_filter, const String& desc_filter);
  };

} // namespace OpenMS