Qvalue Class Reference

Qvalue : contains functions to calculate Qvalues from deconvolution quality score. More...

#include <OpenMS/ANALYSIS/TOPDOWN/Qvalue.h>

Public Types
typedef FLASHDeconvHelperStructs::LogMzPeak	LogMzPeak

Static Public Member Functions
static void	updatePeakGroupQvalues (std::vector< DeconvolvedSpectrum > &deconvolved_spectra, std::vector< DeconvolvedSpectrum > &deconvolved_decoy_spectra)

Static Private Member Functions
static uint	getBinNumber (float qscore, uint total_bin_number)
	get a bin number given qvalue. qvalue is calculated per bin (bin from 0 to 1). More...
static float	getBinValue (uint bin_number, uint total_bin_number)
	get the qvalue corresponding to a bin number More...
static std::vector< float >	getDistribution (const std::vector< float > &qscores, uint bin_number)
	get the Qscore distribution More...
static std::vector< float >	getDistributionWeights (const std::vector< float > &mixed_dist, const std::vector< std::vector< float >> &comp_dists, uint num_iterations=100)
	get the weights of different dummy types. More...

Detailed Description

Qvalue : contains functions to calculate Qvalues from deconvolution quality score.

Member Typedef Documentation

LogMzPeak

typedef FLASHDeconvHelperStructs::LogMzPeak LogMzPeak

Member Function Documentation

getBinNumber()

static uint getBinNumber ( float  qscore, uint  total_bin_number  )

staticprivate

get a bin number given qvalue. qvalue is calculated per bin (bin from 0 to 1).

getBinValue()

static float getBinValue ( uint  bin_number, uint  total_bin_number  )

staticprivate

get the qvalue corresponding to a bin number

getDistribution()

static std::vector<float> getDistribution ( const std::vector< float > &  qscores, uint  bin_number  )

staticprivate

get the Qscore distribution

getDistributionWeights()

static std::vector<float> getDistributionWeights ( const std::vector< float > &  mixed_dist, const std::vector< std::vector< float >> &  comp_dists, uint  num_iterations = 100  )

staticprivate

get the weights of different dummy types.

updatePeakGroupQvalues()

static void updatePeakGroupQvalues ( std::vector< DeconvolvedSpectrum > &  deconvolved_spectra, std::vector< DeconvolvedSpectrum > &  deconvolved_decoy_spectra  )

static

Calculate and perform a batch update of peak group qvalues using Qscores of target and dummy peak groups in deconvolved spectra, when FDR report is necessary.

Parameters

deconvolved_spectra	target deconvolved spectra
deconvolved_decoy_spectra	decoy deconvolved spectra

Referenced by TOPPFLASHDeconv::main_().